In this study, researcher developed a new imaging approach that combines two powerful techniques to solve this problem. First ...

By modeling the central, experimentally verified cell–cell signaling pathways, we show that the cross-talk between negatively selected thymocytes and medullary-tissue cells enables the mouse thymus to ...

The thymus shrinks with age, contributing to a weaker immune system in adulthood. In experiments with mouse models, increasing FGF21 preserved both the size and function of the thymus, allowing ...

The thymus is a crucial training ground for T-cells, the body's "white knights," where they learn to battle the various ...

Utilizing advanced bioinformatics technology, we employed RNA-sequencing to screen key differential genes influenced by the chronic unpredictable mild stress (CUMS) model in the thymus of mice. The ...

A WEHI study could help solve a long-standing mystery into why a key immune organ in our bodies shrinks and loses its function as we get older. The thymus is an organ essential for good health due to ...

Zhao, on Gray’s team, used innovative thick-slice microscopy on mouse thymus tissue to enable the collaborators to see non-functional regions that appear to correspond to the aaTECs Kousa and Dudakov ...

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus. The organoids, derived from mouse thymus tissue, specifically model thymic epithelial ...

Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus. The organoids, derived from mouse thymus tissue, specifically model thymic epithelial ...

The Thymus Rejuvenation project, led by Thymmune Therapeutics, aims to restore damaged or non-functional thymus tissue. Using laboratory methods, scientists can turn cells into different tissue types, ...