thymic tissue does. For binding assays, monoclonal antibodies to human CD18 (L130, mouse IgG1), CD3 (UCTH1, mouse IgG1), CD45 (H130, mouse IgG1), CD71 (M-A712, mouse IgG2a), CD11c (LeuM5 ...

All model parameter estimates were obtained based on published physiological data of thymocyte dynamics and thymus properties in mouse and human ... cells to peripheral lymphoid tissues such as the ...

Conventional T cells that recognize peptide antigens presented by the major histocompatibility complex (MHC) undergo well-characterized processes of antigen receptor rearrangement followed by positive ...

Scientists discovered years ago that the hypothalamus—which helps to manage body temperature, hunger, sex drive, sleep and ...

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical ...

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers discovered that chronic intermittent fasting disrupted the development of ...

A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical ...

An international research team led by scientists at the City of Hope reports that they have demonstrated a way in preclinical studies to boost thymic function after damage in preclinical studies.

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

LOS ANGELES--(BUSINESS WIRE)--A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United ...