Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve ...

The lack of animal models that mimic human disease impedes the study of many pathologies that still lack treatment beyond symptom relief. This is what has happened so far with PURA syndrome, a rare ...

Researchers led by Maike Sander, scientific director of the Max Delbrück Center, have developed a vascularized organoid model ...

Researchers have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather ...

MAIT cells are good fighters. Researchers have found that MAIT cells can respond very quickly to infections. Their speed ...

In doing so, it further protects the CAR T cells and promotes their ability to attack the cancer cells, June explained. This study represents a significant development in the ongoing evolution of ...

The mouse-based study, published in the Journal of Experimental Medicine, uncovered a new way to enhance stem cell-like memory CD8+ T cells following vaccination, pointing to a future where more ...

Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced ...

These cells have been a puzzle, Wu said, because the conventional T FH cells are expected to be nonmobile, and just reside in B cell follicles to help B cells, another immune cell type critical for ...

This highlights the urgent need for innovative therapeutic approaches. CAR T-cell therapy, which has shown remarkable success in hematological malignancies, is now being explored for solid tumors like ...