Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies.

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

T-cell receptor (TCR) signalling is central for the fundamental choice between immunity and tolerance and for regulating T-cell differentiation after exposure to antigen. Signalling circuits ...

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve ...

The lack of animal models that mimic human disease impedes the study of many pathologies that still lack treatment beyond symptom relief. This is what has happened so far with PURA syndrome, a rare ...

Researchers have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather ...

Tumor cells in colorectal cancer exploit an important signaling pathway that normally controls embryo development.