Due to the sudden rupture of the aortic wall, aortic dissection is a life-threatening condition that requires immediate ...

A new study in Nature Communications presents a solution to protein leakage in single-cell proteomics, improving data quality ...

The novelty lies in combining the strengths of both algorithms, achieving better prediction accuracy and reducing errors compared to single-model methods. It provides continuous and scalable SOH and ...

The human alpha cells described in this research will be a useful model to understand diabetic alpha cell dysfunction and to screen for new therapeutics.

Departments of Structural Biology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, United States Developmental Neurobiology, St. Jude Children’s Research ...

Methods: To determine the potential involvement of PXR in the regulation of steroidogenesis, experiments were performed on a wild type (MLTC-1WT) and a Pxr knock-down (MLTC-1PxrKD) mouse Leydig cell ...

1Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California. 2Department of Radiation Oncology, City of Hope Comprehensive Cancer Center, Duarte ...

A cancer immunotherapy known as ipilimumab was able to reduce scar formation and promote tissue regeneration in the lungs of a mouse model of idiopathic pulmonary fibrosis (IPF). Treatment boosted the ...

We demonstrated the dual functions of transforming growth factor-beta-activated kinase 1 (TAK1) in microglial-mediated neuroinflammation in the rd10 mouse model of retinitis pigmentosa (RP).

The output matrix from this process was further refined through a second-layer GLM algorithm to construct the stacked ensemble model and determine each participant's cancer probability score. A, ...