The finding, in a mouse model of the human brain, focuses on specific cells called pericytes and reveals that they play a previously unknown role in brain health. Pericytes secrete a substance that ...

When the team blocked, or inhibited, the action of Fli-1 in a mouse model of Alzheimer's disease, the memory of the mice improved. Blocking the protein also stopped immune cells from leaking into ...

Due to the sudden rupture of the aortic wall, aortic dissection is a life-threatening condition that requires immediate ...

They also used a second model with genetically modified mice that deleted the protein TDP-43 only from endothelial cells, not other cells in the brain. Both mouse models showed clear signs of ...

They do so by using MHC-II to instruct a different subset of CD4 + T RM cells in the airways to produce a cytokine IFN-gamma, which then potently suppressed inflammation in this mouse model of ...