Research led by the Department of General and Visceral Surgery, Faculty of Medicine, University of Freiburg, Germany has ...

Bile acids affect the expression of a chemokine ligand by liver sinusoidal endothelial cells, ... In a series of experiments in mouse models, ...

Cholelithiasis and dilated common bile duct in mdr2 knockout (mdr2KO) mouse seen with magnetic resonance (MR) imaging and confirmed by anatomic dissection. ( a ) Gallstones are seen as 0.35 mm ...

The drug improved bile composition and reduced inflammation and fibrosis in a mouse model by targeting two ABC transporters, ABCB4 and BSEP. Rectify Pharma is using its ABCs to treat PSC.

In studies in mice, researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting ...

Bile acid receptors have become attractive therapeutic targets for liver disease and metabolic disorders. ... but not mouse, bile contains substantial amounts of FGF19, ...

In the distal ileum, FXR, activated by bile acids, induces expression of the FGF19 gene in humans. ... The authors caution that human and mouse bile acid profiles differ in important ways.

Bile duct cancer is a rare but aggressive form of cancer, affecting just over 2,000 people in the UK every year. However, incidences of bile cancer are steadily increasing every year – with some ...

Bile duct cancer is a rare but aggressive form of cancer, affecting just over 2,000 people in the UK every year. However, incidences of bile cancer are steadily increasing every year – with some ...