Monocytes are a principal component of the body’s innate immune system, and the new research looks at how sleep quality ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Poor sleep quality alters immune function, increasing inflammation and disease risk. One night of sleep loss can mimic immune ...

Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering ...

One key takeaway is that sleep deprivation triggers an increase in nonclassical monocytes (NCMs), immune ... and can impair cognitive function, mood, and overall quality of life.

In the pathogenesis of atherosclerotic diseases, such as coronary artery disease (CAD), monocytes not only serve as the initial sensors of endogenous and exogenous pathogenic factors, but also ...

More information: Fatema Al-Rashed et al, Impact of sleep deprivation on monocyte subclasses and function, The Journal of Immunology (2025). DOI: 10.1093/jimmun/vkae016 ...

It’s also known that poor health outcomes can be driven by chronic inflammation but the direct influence of sleep on circulating immune cells, such as monocytes, is not as well understood.

Monocytes play an important role in innate inflammatory responses and may be modulated by bacterial translocation. Our aim was to investigate the subset distribution and function of circulating ...