Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and selectively inhibits monoamine oxidase type B (MAO-B). Rasagiline demonstrates complete and selective ...

Despite the replacement of the monoamine hypothesis of depression with a more comprehensive understanding of multiple influencing factors in the pathology of depression, it is clear that elevating ...

“The [majority] explained that ‘[t]his analysis does not usurp the province of the jury, nor does it involve this court deciding disputes of fact,’ but instead ‘involves the gatekeeping ...

But iron itself is only part of the picture. Your body also needs cofactors – supporting nutrients – to transport, store and properly utilise iron. For example, copper is vital for ...

Neurobiogen Co Ltd. has synthesized monoamine oxidase-B (MAO-B) inhibitors reported to be useful for the treatment of Parkinson’s disease.

Redox signaling refers to the specific and usually reversible oxidation/reduction modification of molecules involved in cellular signaling pathways. In the heart, redox signaling regulates several ...

Changes in driving pressure were used to measure active changes in venous tone. Administration of tranylcypromine greatly reduced the activity of monoamine oxidase in the vein and increased its ...

Sulfite oxidase (SO) catalyzes the physiologically critical conversion of sulfite to sulfate. Enzymatic activity is dependent on the presence of the metal molybdenum complexed with a ...

State Key Laboratory of Natural Medicines, China Pharmaceutical University, 639 Longmian Avenue, Jiangning, Nanjing 211198, China Laboratory of Chemical Biology, School of Life Science and Technology, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Defects in mitochondrial oxidative metabolism ...