During mitosis, the chromatin undergoes a dynamic reorganization important for faithful chromosome segregation. Here the authors show that the DEAD-box RNA helicase eIF4A1/2 regulates the ...

The authors use elegant time-dependent microscopy reporter assays in immortalized tumor cell models to show that HIV-1 Vif causes a pseudo-metaphase arrest rather ... organization of chromosomes ...

It also touches on the implications of mitosis in healing and the potential consequences of its disruption, such as cancer or damage from radiation. Keywords mitosis, cell division, chromosomes, DNA, ...

FIGURE 1. Schematic view of the human UBAP2L protein and its domain organization. UBAP2L (1087 AA) is composed of a Ubiquitin-associated domain (UBA, yellow), an Arginine-Glycine-Glycine (RGG, green) ...

1997). In brief, the testes were decapsulated and then incubated with approximately 10 volumes of HBSS solution containing 1 mg/ml collagenase IV (17104–019, Gibco, United States) and 1 mg/ml DNase I ...