Mitochondrial dynamics protein 49 kD (M:D49) and mitochondrial dynamics protein 51 kD (M:D51), which are located in the mitochondrial outer membranes, form division-inducing rings around mitochondria.

Mitochondria have a fundamental role in regulating metabolic pathways, and tight control of mitochondrial functions and dynamics is critical to maintaining adequate energy balance. In complex ...

The fusion of two or more mitochondria, and the fission of a mitochondrion into two units are common phenomena known as "mitochondrial dynamics" and both processes are necessary for the proper ...

Now, collaborative research co-led by Dr. Julie St-Pierre's lab at the Faculty of Medicine sheds new light on the mysteries of mitochondrial dynamics and its likely role in the metastatic progress ...

Mitochondria are subcellular organelles that coordinate numerous metabolic reactions, including those of the respiratory complexes that produce the ATP that powers cellular reactions. They have ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

The central goal of research in the Mears Lab is to investigate proteins that regulate mitochondrial dynamics. Mitochondrial dynamics has recently come to the forefront as a therapeutic target in ...

Intermittent fasting in humans may increase mitochondrial dynamics and thus increase lifespan, Singh said, adding this idea still requires more research. Future research in this avenue may lead to ...

Problems with mitochondrial dynamics are particularly implicated in schizophrenia, along with other disruptions of mitochondrial function, including lack of enzymes essential in the energy ...

Precise Mitochondrial Calcium Dynamics Monitoring: TurCaMPb's pH insensitivity and inverse calcium response allow for exact measurements of calcium changes within mitochondria, even in pH-variable ...