Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a ...

A newly discovered mechanism that leads to liver dysfunction may be a key factor in type 2 diabetes and other metabolic ...

Research reveals that such overproduction is not random, but rather occurs at a specific site in one mitochondrial enzyme, opening the door to targeted therapies for metabolic diseases.

Mitochondria convert chemical energy from food into a form of energy the cell can use. This process is called oxidative phosphorylation. The Krebs cycle produces a chemical called NADH.

The study, titled "Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients with Type 2 Diabetes," was recently published in the Journal of ...

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate ...

Mitochondrial diseases affect approximately ... activator-like effector nucleases (mpTALENs)—specialized enzymes that can selectively target and cleave specific DNA sequences.

I found out about Mitolyn, a natural weight loss supplement inspired by Harvard research, and it stood out to me. Instead of ...

However, it has recently been shown that faulty marking of damaged mitochondria prevents their degradation. This is caused by certain key enzymes of mitophagy, which are pathologically altered in the ...