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In all eukaryotes, a microtubule-based structure known as the spindle is responsible for accurate chromosome segregation during cell division. Spindle assembly and function require localized ...
Mutation of Lis1, a key dynein regulator, can lead to the rare mental developmental disorder lissencephaly, or “smooth brain, ...
Initiation of mitosis is accompanied by chromosome condensation and nuclear envelope breakdown; this coincides with disassembly of interphase microtubule and actin arrays and assembly of the ...
thus increasing the free energy barrier that needs to be overcome to form a straight microtubule lattice. Electron Tomography Confirms Predicted Structural Differences at the Ends of Growing and ...
Department of Chemistry, Binghamton University, State University of New York, Binghamton, New York 13902, Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, ...
Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells
Both impaired actin reorganization and attenuated microtubule filament formation inhibit cancer cell migration and invasion, thereby preventing metastasis. On the other hand, failure of spindle ...
Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...
Life on Earth possesses an exceptional ability to self-reproduce, which, even on a simple cellular level, is driven by ...
The assembly prioritized Indigenous voices, recommending opportunities for land use and cultural preservation. The final report will be presented to the City Council for review and potential action.
Just one day after Gov. Kathy Hochul announced she clinched a budget deal, the Democratic-controlled state Assembly spent hours debating — and then passing — a bill that would legalize what ...
The National Assembly has urged the Supreme Court to dismiss the suit filed by 11 Peoples Democratic Party governors challenging the declaration of a state of emergency in Rivers State.
Stellantis outlined its production schedule through July for Windsor Assembly Plant to its suppliers and Unifor Local 444 Monday and confirmed to the Star it still plans on making the facility a ...
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