Mutation of Lis1, a key dynein regulator, can lead to the rare mental developmental disorder lissencephaly, or “smooth brain, ...

thus increasing the free energy barrier that needs to be overcome to form a straight microtubule lattice. Electron Tomography Confirms Predicted Structural Differences at the Ends of Growing and ...

Both impaired actin reorganization and attenuated microtubule filament formation inhibit cancer cell migration and invasion, thereby preventing metastasis. On the other hand, failure of spindle ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

Life on Earth possesses an exceptional ability to self-reproduce, which, even on a simple cellular level, is driven by ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Brief ciprofloxacin exposure in humans drives antibiotic resistance evolution in gut bacteria through selective sweeps, particularly involving DNA gyrase mutations, which persist long after ...