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A phase 2 study of olaparib in IDH1 and IDH2 mutant advanced chondrosarcomas and other solid tumors. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not ...
Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome ...
Excessive sequestration of KEAP1 into phase-separated p62 bodies under conditions of impaired autophagy drives persistent ...
In a new study out this week, scientists report that a combination of two existing cancer drugs — rapamycin and trametinib — ...
The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release ...
A cocktail of FDA-approved cancer drugs, trametinib and rapamycin, boosts the lifespan of lab mice by 30% and might help ...
Announced during Nintendo Direct March 2025, Marvel Cosmic Invasion is a retro brawler from Tribute Games, developer of the much-loved Teenage Mutant Ninja Turtles: Shredder's Revenge. It’s due ...
Liver diseases are any diseases that affect the functioning of the liver. Liver diseases can be inherited (such as Wilson disease and alpha 1-antitrypsin deficiency) or acquired (for example ...