Researchers say they are exploring therapeutic options to block fatty acid accumulation and immunosuppressive signals between ...

Cutaneous melanoma, the most aggressive form of skin cancer, is characterized by its accumulation of a large number of ...

Melanoma cells, the most aggressive form of skin cancer, produce a protein that blocks the recognition and removal of the ...

An international research group has developed a new method to help the immune system recognise and attack cancer cells by ...

A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop ...

Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy.

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, ...

Now we know that the treatment works in principle in mice, researchers can continue to develop this immunotherapy to make it suitable for people, as well as to understand the full effect it could have ...

Results provide proof-of-concept that ERK pathway reactivation might be an effective, biologically based therapy to prevent anthrax-induced lethality.

In mouse models, the approach has been proven effective in activating immune cells to target and destroy cancer cells, inhibiting tumour growth. Combining this method with existing immunotherapy has ...

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept ...