Certain alleles, called meiotic drivers ... to extinction—a paradox that has been recognized for a long time." Meiosis is a key process underlying sexual reproduction. This is when cells ...

Meiosis is the generation of germ cells (eggs and sperm). In meiosis, DNA replication is followed by two division cycles: meiosis I, which segregates homologous chromosomes and meiosis II, which ...

During meiosis, sister chromatids produced by chromosome duplication are held together by Rec8, a meiosis-specific cohesion protein. Rec8 joins the whole length of the sister chromatids together ...

This phenomenon is known as multilocus inherited neoplasia alleles syndrome (MINAS), which has been potentially linked to more severe clinical manifestations. Objective To determine the prevalence and ...

Correspondence to Fenne Wouters, Department of Rheumatology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands; f.wouters{at}lumc.nl Objectives The human leukocyte antigen-shared ...

*Department of Clinical Genetics, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands †Department of Clinical Genetics, Erasmus University Medical Centre Rotterdam, ...

kDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands lDepartment of Biomedical Data Sciences, Section Molecular Epidemiology, Leiden University Medical ...