In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

Disposable DNA diagnostic sensors from MIT stay accurate for two months at 150 °F, cutting test costs to 50¢ and removing ...

Using an inexpensive electrode coated with DNA, MIT researchers have designed disposable diagnostics that could be adapted to ...

But the research topic is, for obvious reasons, controversial. Scientists have largely steered clear of trying to create full ...

Artificial human DNA, or synthetic DNA (synDNA), would be made without biological parents by instead using chemicals. SynHG ...

Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

DNA 'glue' could help prevent and treat diseases triggered by aging by Georgia Gowing, Macquarie University edited by Gaby Clark, reviewed by Robert Egan Editors' notes ...

New blood tests can detect cancer recurrence earlier than traditional scans, potentially giving doctors and patients crucial information to make decisions about treatment. But more studies are needed ...

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix ...

Journal Reference: Parth Rakesh Desai, John F. Marko. Molecular Crowding Suppresses Mechanical Stress-Driven DNA Strand Separation. Biophysical Journal, 2025; DOI: 10.1016/j.bpj.2025.04.024 ...