Chinese researchers recently uncovered molecular evidence supporting Lamarckism—a long-debated theory from the early 19th ...

A team of University of Kentucky Markey Cancer Center researchers has found the mechanism that grants prostate cancer resistance to enzalutamide, a frequently used drug. The article is published ...

Hopefully, through understanding the insights below, applicators will be better motivated and cognitive of integrative practices that we usually preach, which delay insecticide resistance. The concept ...

The new large-scale study by researchers from the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), Open Targets and collaborators used CRISPR gene editing to map the ...

In the beginning of introduction of antibiotics into clinical practice it was presumed that the resistance mechanisms against antibiotics ... has been essentially based on the Paul Ehrlich’s concept ...

Pharmacokinetics (PK) and Pharmacodynamics (PD): Initial data demonstrating dose-dependent bioavailability and degradation of BRAF V600E protein support CFT1946 proof of mechanism ... of early proof ...

However, a new Moffitt Cancer Center study, published in Cell Reports Medicine, uncovers the mechanisms that drive this drug resistance, offering new avenues for potential treatments. Moffitt ...

Though osimertinib is the preferred frontline approach to treatment for those with non-small cell lung cancer with classic EGFR mutations, acquired resistance mechanisms invariably develop. Although ...

The tumor microenvironment, tumor immunogenicity, antigen presentation, and classic oncologic pathways play roles in response and resistance to immune checkpoint blockade. By understanding resistance ...

We find no effect on stimuli coverage, but a negative impact on map unfolding, dependant on the intensity of the abnormality, but not the time of onset. We analyze sensory issues by introducing the ...

Telling these stories is an act of resistance ... the concept of the evil eye and curses runs deeper in this narrative. Etaf explores the idea of Palestinians being cursed and how the belief in the ...

This breakthrough discovery of RlmN as a stress sensor has revealed a new mechanism of antimicrobial resistance that can be targeted for drug development. (L to R) SMART researchers Dr Cui Liang ...