SAN FRANCISCO, March 27, 2025 (GLOBE NEWSWIRE) -- Third Harmonic Bio, Inc. (Nasdaq: THRD), a biopharmaceutical company focused on advancing the next wave of medicine for inflammatory diseases, today ...

Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body.

Researchers have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a promising new approach to improving treatment outcomes.

Mast cells, which are abundant in the airways of asthmatic individuals, act as first responders to viral infections by ...

The global mast cell tumor treatment market is on a strong growth trajectory, with market projections estimating a valuation of USD 7,836.4 million by 2034. This reflects a steady CAGR of 3.4% from ...

Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, ...

The innate immune system: Components of the innate immune system are being recognized to play a role in MS. Masitinib is a mast cell inhibitor currently being studied. LINGO-1 antagonist is ...

At the recent AAAAI/WAO meeting, Blueprint Medicines Corp. presented the in vitro and in vivo characterization of BLU-808, a selective inhibitor of wild-type KIT, a transmembrane receptor tyrosine ...

This study demonstrated that combining JAK2-selective inhibitors with KIT-targeting TKIs improved efficacy by significantly enhancing their cytotoxic effects, suggesting a synergistic approach for ...

Mucosal mast cell number and activation were determined by quantifying ... in T-PER buffer and protease and phosphatase inhibitor cocktail (Invitrogen), following the manufacturer's recommendations.