Find out what you need to know about mast cell tumors in cats. Learn about the causes, symptoms, treatment, medication, and prevention of mast cell tumors.

These factors activate mast cells to release mediators, such as Try and Hist, that can activate the corresponding receptors PAR-2 and H1. Concurrently, PAR-2 and H1 activation on C-fibers leads to ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown in mice: mast cells function as a sensor ...

Alcohol withdrawal headache-related behaviors were absent in mice lacking the mast cell receptor MrgprB2.

Although treatment with high-dose corticosteroids can reduce mast burden and improve symptoms such as pain, congestive heart failure, and cytopenia in patients with MCL, their effects are frequently ...

Reference Horiuchi, Y. Importance of mast cell activation control for preventing scar formation in severe acne. J Clin Aesthet Dermatol. 2023;16 (3):30-31.

– Data provide insights on the signaling pathways involved with AK006 mast cell inhibition –– AK006 has a distinct mechanism of action that leads to broad inhibitory effects on mast cells ...

Mast cell activation syndrome (MCAS) is a condition where the mast cells are inappropriately triggered.

Blueprint Medicines Corporation (Nasdaq: BPMC) today announced data presentations reflecting its ongoing efforts to innovate the treatment of mast cell-driven diseases. The presentations include ...

These factors can activate mast cells to release proinflammatory mediators and some of them, for example, histamine, tryptase and nerve growth factor, can stimulate sensory C-fibers.