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Rome (CNN) — Following the death of Pope Francis, a cardinal from the United States has become acting head of the Vatican until a new pontiff is elected.

The certificate officially lists the cause of death as cerebral stroke, coma, and "cardiocirculatory collapse." Vatican City's director of the health, Prof. Andrea Arcangeli, signed the document.

Pope Francis died Monday at age 88. The Vatican said Francis suffered a stroke which led to a coma and his heart to fail, as he recovered from a five-week hospitalization for double pneumonia.

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Here, we investigated the association of hypoxia response markers with EMI in the U.S. population. Hypothesis: Individuals with EMI show a compensatory response suggestive of subclinical hypoxia.