Gammagard Liquid ERC is a ready-to-use formulation with low IgA content designed to ease administration burden by removing the need to reconstitute.

Celiac disease affects 0.6 to 1.0% of the population worldwide, 2,3 with wide regional differences in Europe (e.g., the prevalence is 0.3% in Germany and 2.4% in Finland) for reasons that are ...

The tissue transglutaminase IgA test is the most sensitive and effective method of celiac disease testing. It shows positive results in almost 98% of people with celiac disease who eat gluten.

In addition, transglutaminase IgA is very low in children in whom only lymphocytic enteritis is observed. On the other hand, Marsh I can represent >50% of cases in adults.

Total serum IgA: This checks for IgA deficiency, a condition in 2% to 3% of those with celiac disease that may lead to a false negative result in tTG-IgA or EMA tests.

A patient should be screened with an IgA tissue transglutaminase antibody and a total IgA level. In those patients with a low IgA level, an IgG ttg and IgG antigliadin antibody should be tested. In ...

In adults, the most common symptoms of celiac disease are stomach problems, like gas and diarrhea. A tissue transglutaminase IgA test, or tTg-IgA test, is an effective method used in the diagnosis ...

IgA nephropathy is an autoimmune disease of the kidneys. It's associated with several health conditions, such as lupus, celiac disease, and kidney failure.

For adults with suspected celiac disease and no IgA deficiency, ... Limitations include a lack of data on IgA-deficient participants, a low number of participants in some subgroup analyses, ...

Reporting online in Lancet Gastroenterology and Hepatology, Ciacci's group said the positive predictive value of the blood test was 95.9% (95% CI 92-99.8) and the negative predictive value was 90. ...

Celiac disease can cause an itchy, blistering rash, known as dermatitis herpetiformis. The rash will typically improve with a gluten-free diet. Learn more here.

If there is a low pretest probability, testing can begin with IgA and TTA Ab testing. Note that about one in 500 people in the U.S. are IgA deficient, which could lead to a falsely low TTA Ab test.