Excerpted with permission from Our Future is Biotech: A Plain English Guide to How a Tech Revolution is Changing Our Lives ...

The blood-brain barrier (BBB) restricts systemically delivered therapeutic antibodies into the brain. Here the authors engineer antibody Fc region to promote the binding to BBB expressed neonatal ...

The FDA has said it intends to reduce or replace animal testing of some medicines, including monoclonal antibodies, with other methods that it hopes will be more relevant to human physiology.