Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

Glucose levels influence physiology and adaptation rates under replication stress, yet core adaptive mutations remain ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

Creating genomes from DNA is hugely important for managing threatened species—understanding their past and how they have ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed ...

But scientists are increasingly interested in ‘all in one’ tools for interpreting DNA sequences. AlphaGenome is one such model.

Origin firing is the initiation of DNA replication that takes place at specialised start sites, or replication origins, where the DNA first has to be opened up and unwound, before DNA synthesis ...

Plant RNA viruses pose a significant threat to global agriculture, affecting a vast array of crop species and leading to ...

Genetic testing company 23andMe never hit on a sustainable business model and went bankrupt. Now, it's being sold to a non-profit launched by the co-founder, delaying addressing data privacy concerns.

Further validation using Illumina sequencing data substantiated a strong correlation between model scores and sequence error-proneness, emphasizing the model’s applicability. The LQSF method marks a ...

AlphaGenome scores mutation effects across coding and non-coding DNA, bringing gene insights to the base-pair level.

Bulk rheology measurements on concentrated monodisperse ring–linear DNA mixtures are reported for the first time. The entanglement behavior of the ring–linear DNA mixtures (with 15 and 50% linear ...