The ensemble binding curve is the sum of individual binding curves, which are shifted relative to one another along the ligand concentration axis. The ensemble curve starts to rise before the ...

Figure 2 also includes the raw association and dissociation kinetics of ligand binding, as well as the binding curve observed when using the ligand at the median concentration of 15 nM.

Force-distance curve-based atomic force microscopy ... For the detection of specific binding sites FD-based AFM requires tethering of a ligand to the AFM tip. While contouring protein complexes ...

The authors of the paper developed a program that takes into account the denaturation and ligand binding equilibria and allows one to predict the DSC curve from the known binding constants and protein ...

Researchers now offer a simplified method they call ProteinReDiff that uses artificial intelligence to speed the redesign of ligand-binding proteins. In biology, the binding of cellular proteins ...

Based on recent FDA comments, Gilead's revolutionary Sovaldi drug will virtually eliminate demand for Promacta, which is Ligand's largest royalty generating asset, accounting for as much as 72 ...

Researchers led by Truong Son Hy, Ph.D., from the University of Alabama at Birmingham, offer a simplified method they call ProteinReDiff that uses artificial intelligence to speed the redesign of ...