Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neoantigen vaccine is a promising breakthrough ...

School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, College Green, Dublin 2 D02 PN40, Ireland Trinity Translational Medicine Institute, Trinity College ...

Cells expressing ER-FlucDM-eGFP, ER-eGFP, ER-HaloDM-eGFP, ER-FlucWT-eGFP, and ER FSHR-FlucDM-eGFP, ER-FlucDM-mCherry were generated through lentivirus transduction and selected with 5 μg/mL puromycin ...

Diabetes. 2005;54(5):1264-1276. Interestingly, only restoration of DAF-2 in neurons was sufficient to restore lifespan and reproduction of DAF-2 knockouts to wild-type values, and neuron-specific ...

Viral gene delivery is a ubiquitous laboratory technique with a myraid of uses. Understanding the basics of gene delivery workflows, from vector selection and cloning to transduction, is a fundamental ...

An analysis of skull and vertebrae fossils suggests that an early relative of giraffes butted heads to compete for mates, which may reveal why modern giraffes are so throaty.

Angiogenesis requires the temporal coordination of the proliferation and the migration of endothelial cells. Here, we investigated the regulatory role of microRNAs (miRNAs) in harmonizing angiogenesis ...

Arginine transport through the plasma membrane of mammalian cells is mediated by eight different ... Out of five different plasmids encoding shRNAs to downregulate CAT-1 upon lentiviral transduction, ...

16 For simultaneous double lentiviral transduction, cultures divided beyond p50, except that ipnNF09.4 was only taken to p47, but did not show signs of senscence at that point, and sipnNF95.12B ...

The bacterial cre protein uses the lox sites for site-specific recombination in mammalian cells (Sauer and Henderson ... of optogenetics will be its use in humans. Although lentivirus has a limited ...