American visceral Leishmaniasis; Leishmania infantum; deletion; ecto-3’-nucleotidase/nuclease; adaptation; evolutionary process 1 WHO - World Health Organization ...

Leishmaniasis are a group of neglected tropical vector-borne diseases caused by an obligate intracellular protozoan parasite of the genus Leishmania. Currently, standard chemotherapy has challenges ...

Therefore, anti-leishmanicidal peptides from insect sources encompass a safe alternative to control Leishmania infection, once they are highly effective, but not as harmful as the current used drugs.

Extant protein-coding sequences span a huge range of ages, from those that emerged only recently to those present in the last universal common ancestor. Because evolution has had less time to act on ...