Our previous studies demonstrated overexpression of the mitotic spindle protein kinesin (HSET) and the anti-apoptotic Bcl-2 in taxane resistant human prostate cancer cells, C4-2BDR. This study aims to ...

Credit: TippaPatt / Shutterstock. US-based biopharmaceutical company Accent Therapeutics has dosed the first subject in an open-label Phase I/II trial of ATX-295, an oral kinesin family member 18A ...

[Editors' note: this paper was reviewed by Review Commons.] The two identical motor domains (heads) of dimeric kinesin-1 move in a hand-over-hand process along a microtubule, coordinating their ATPase ...

These observations demonstrate how work output from curling protofilaments can be tuned and suggest evolutionary conservation of the amount of curvature strain energy stored in the microtubule lattice ...

Plant organ shape is determined by the spatial-temporal expression of genes that control the direction and rate of cell division and expansion, as well as the mechanical constraints provided by the ...