Figure 1: Structure and motility models of KIF5 and KIF1A. The kinesin motor domain is composed of a single globular catalytic core and a short strand 'neck linker'. The catalytic core contains ...

Edited by Ken A. Dill, Stony Brook University, Stony Brook, NY, and approved September 26, 2019 (received for review August 6, 2019) ...

we demonstrate that huntingtin phosphorylation promotes anterograde transport. Conversely, when huntingtin is not phosphorylated, kinesin‐1 detaches and vesicles are more likely to undergo retrograde ...

Abstract: The cytoskeletal motor protein kinesin-1 has been successfully used for many nanotechnological applications. Most commonly, these applications use a gliding assay geometry where ...

This approach is particularly useful because it enables the use of the well-understood PEG−silane chemistry on SiO 2 for the blocking of kinesin, whereas the gold tracks allow possible electrical ...

Using a combination of live imaging and photo-kinetic assays in an in vitro culture system, they provide convincing evidence that kinesin-1-mediated microtubule sliding, which plays critical roles in ...

Retrograde amnesia is the inability to remember past experiences. It's different than anterograde amnesia, which is the inability to form new memories. Types of retrograde amnesia have different ...

† Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan ‡ Graduate School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, ...

Vlad – stock.adobe.com Named for the lord of the underworld himself, Pluto will remain retrograde through October 13th, heralding a time of introspection and shadow dancing. Because Pluto rules ...

Pluto oversees the cycles of birth and death. Find out what Pluto retrograde means for you in 2025. Haramis Kalfar - stock.adobe.com Pluto, our petite power planet of primordial urges ...

Pluto stations retrograde on May 4, 2025, beginning a powerful new era for four zodiac signs that lasts until the planet stations direct on October 13, 2025. The transit will impact fixed signs ...