Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

The thymus is a crucial training ground for T-cells, the body's "white knights," where they learn to battle the various diseases they may encounter. Thymic function shrinks to nearly nothing as we age ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ-PKAc fusion oncoprotein. However, the underlying mechanism of DNAJ-PKAc’s ...

Nature has developed a unique structure as a scaffold for almost all nerve cells: the membrane-associated periodic skeleton ...