A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

Mutation of Lis1, a key dynein regulator, can lead to the rare mental developmental disorder lissencephaly, or “smooth brain,” where the brain’s surface lacks the normal folds and grooves, for which ...

Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to carting protein instructions to disposing of cellular garbage. These highways ...

These members are referred to as histone deacetylases (HDAC) 1–11. HDAC1, HDAC2 and HDAC3 are deacetylase subunits of multiprotein complexes that are crucial for chromatin modification and ...

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

Type 1 diabetes (also known as diabetes mellitus) is an autoimmune disease in which immune cells attack and destroy the insulin-producing cells of the pancreas. The loss of insulin leads to the ...

Monaco is an iconic Formula 1 destination, renowned for its history and opulence. Qualifying is always dramatic here because poor grid position can make or break a driver's race. Join Steve Jones ...

Please Note: All times UK. Tables are subject to change. The BBC is not responsible for any changes that may be made. Copyright © 2025 BBC. The BBC is not ...

Real time quote data is not available at this time. *Data is provided by Barchart.com. Data reflects weightings calculated at the beginning of each month. Data is subject to change. **Green ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Edited by Ken A. Dill, Stony Brook University, Stony Brook, NY, and approved September 26, 2019 (received for review August 6, 2019) ...