In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut ... "As the organoid's lumen volume decreases, the tissue ...

The use of the heterogeneous and ill-defined 3D cell culture platform Matrigel has facilitated organoid culture with impressive ... and bond formation to study how intestinal stem cell colonies ...

Model more closely replicates natural environment of the pancreas, which will be essential for studying diabetes and ...

"With such an organoid ... digestive enzymes and the endocrine cells produced hormones." Using these organoids, the researchers discovered new information about how the pancreas develops. "The ...

So when Amanda Andersson-Rolf, a postdoctoral researcher in Hans Clevers’s group at the Hubrecht Institute, set out to build a better pancreatic organoid ... constant self-renewal like the intestine.

Baseline culture conditions are sufficient for the growth of porcine intestinal mucosal organoids. The company believes it has established stem cell organoid cultures from anal skin for the first ...