Stem-cell derived organoids provide the perfect mixture of cells to rebuild damaged intestines.

In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut ... "As the organoid's lumen volume decreases, the tissue ...

Advances in CRISPR ... cells into induced pluripotent stem cells (iPSCs) and other advances in tissue engineering have enabled scientists to grow a range of different tissues, including mini guts, ...

A team of CiRA researchers has uncovered the crucial role of EIF3D—a protein translational regulator—in primed pluripotency.

It is unclear which intestinal epithelial cell-derived cytokines can precisely regulate intestinal stem cell (ISC) commitment toward specific mature cells. Here, authors identify an epithelial ...

"Our findings suggest the Myc 2-540 super-enhancer region serves as a genetic link between regeneration and tumorigenesis, it is essential for activating stem ... intestinal cells in such organoid ...

Organoids are made to model human organs and are promising for research and therapy, but there are limitations to their growth and function. A recent study by researchers at The University of Tokyo ...

He works in collaboration with the lab of Matthias Zilbauer at the Cambridge Stem Cell Institute, where he completed his ... During his PhD, Dennison gained expertise in the intestinal epithelium and ...