In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut ... "As the organoid's lumen volume decreases, the tissue ...

Advances in CRISPR ... cells into induced pluripotent stem cells (iPSCs) and other advances in tissue engineering have enabled scientists to grow a range of different tissues, including mini guts, ...

Intestinal organoids ... and reproducibility challenges in organoid systems. In a recently published Science paper, 1 his team described how they developed a biomaterial tissue scaffold that allows ...

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study by researchers at The University of Tokyo ...

Desai uses human pluripotent stem cells to grow pancreatic ductal and acini-like cells as mini ‘organs’ called – Organoids. This organoid technology provides us with an invaluable tool to investigate ...

His research aims to identify the role of extracellular vesicles from intestinal epithelial cells (IEC-EVs) in the development of acute graft-versus-host disease (aGvHD) following allogeneic stem ...

He works in collaboration with the lab of Matthias Zilbauer at the Cambridge Stem Cell Institute, where he completed his ... During his PhD, Dennison gained expertise in the intestinal epithelium and ...

A recent study found that placenta-derived IL1 under hypoxic conditions, can greatly increase growth of human stem cell-derived liver ... promising route to improve organoid models and ...