The interaction of Mia40 with Erv1/ALR is central to the oxidative protein folding in the intermembrane space of mitochondria (IMS) as Erv1/ALR oxidizes reduced Mia40 to restore its functional state.

Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the United States and many developed nations. Two major age-related arterial phenotypes, large elastic artery ...

Department of Chemistry, “Sapienza” University of Rome, P.O. Box 34-Roma 62, Piazzale A. Moro 5, I-00185 Roma, Italy ...