3–6 Mice that are deficient in either interleukin-10 or interleukin-10 receptor 2 have been shown to have severe enterocolitis, 26–28 a finding that underscores the pivotal role of interleukin ...

Interleukin (IL)-10 is an important immunoregulatory cytokine that mediates its effects via a transmembrane receptor complex consisting of two different chains, IL-10R1 and IL-10R2. While IL-10R2 ...

9,10 The history of this soluble interleukin-2 receptor, also known as sIL-2R, sCD25, sTAC, sIL2R, or IL-2RA, dates back to 1985 when it was initially described as actively released by activated ...

R denotes receptor. Interleukin-23 can expand a population ... which resemble regulatory T cells and produce interleukin-10 and interferon-γ. The interaction with Tr1 cells may allow interleukin ...

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL-6R). Inhibiting the entire receptor complex prevents IL-6 ...

Five other patients with DLBCL had lymphoma that had relapsed 10 months or less after ASCT as their last treatment ... Fig 2. Chimeric antigen receptor (CAR) targeting CD19 (CAR-19) T cells eradicated ...