suggesting that cationic bovine serum albumin is pathogenic through binding to the anionic glomerular capillary wall and in situ formation of immune complexes, as shown in experimental models.

The pathogenetic links between viral infection and renal disease are often difficult to establish. The criteria for proving causality are complex and include (besides recognition of the clinical ...

Clinical trial to evaluate the safety and efficacy of YK012 in primary membranous nephropathy- Globally, this is the first bispecific CD19-directed CD3 T cell engager immunotherapy for this autoimmune ...

The review examined the potential of combining checkpoint blockade therapy within situ vaccination as ... considerable heterogeneity and complex mechanisms of immune evasion.

--(BUSINESS WIRE)--BostonGene, a leading provider of AI-based molecular and immune profiling solutions ... and Director of the Multiparametric In Situ Imaging Laboratory at Weill Cornell Medicine ...

The cytokine interleukin-15 (IL-15) plays a crucial role in the immune system by affecting the ... ANKTIVA is a first-in-class IL-15 agonist IgG1 fusion complex, consisting of an IL-15 mutant ...

Cowpea mosaic virus, when injected into cancerous tumors, stimulates the immune system to attack and ... anti-tumor impact when used as an in situ vaccine to treat cancer. Commercial development ...

A research group presented a molecular sensor with a microbead format for the rapid in-situ detection of harmful ... of small molecules dissolved in complex biological fluids.

The approach is called in situ vaccination, and it can take many forms such as a virus or targeted radiation. What they all have in common is that they are delivered directly into a tumor to help the ...

These work together to train the immune system to better recognize a tumor cell when it sees one, and take a more active role in hunting them down throughout the body and killing them off.

Submission is based on the ongoing QUILT 3.032 study in which 100 patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer with carcinoma in situ (NMIBC CIS ...