Clinical trial to evaluate the safety and efficacy of YK012 in primary membranous nephropathy- Globally, this is the first bispecific CD19-directed CD3 T cell engager immunotherapy for this autoimmune ...

The Blood In situ Tracking (SENSBIT) system remained fully functional for up to a week when implanted directly into the blood ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release ...

Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently ...

Intestinal inflammatory diseases are mediated by dysregulated immune responses to undefined luminal antigens. Feeding hen egg-white lysozyme to mice expressing a transgenic T-cell receptor that ...

These reactions generally occur after prior development of an immune response to a hapten–carrier complex. On subsequent encounter with the drug, a hapten–carrier complex is formed again ...

Viruses that cause chronic infection influence immune cells to produce predominantly anti-inflammatory cytokines, such as interleukin-10 (IL-10) and transforming growth factor-β (TGFβ), and they ...

Rheumatic diseases are complex multisystem, immune-mediated disorders encompassing conditions like rheumatoid arthritis, ...