This finding initiated decades of extensive immunochemical studies of immunoglobulin structure and function ... been used to study the regulation of IgA switching in Warren Strober's laboratory.

Its lead asset, JADE-001, targets the cytokine anti-A PRoliferation-Inducing Ligand (APRIL) for immunoglobulin A (IgA) nephropathy ... regarding the ownership structure of the combined company ...

Structure of (A) IgG; (B ... (2003) Characterization of human class-switched polymeric (immunoglobulin M [IgM] and IgA) anti-human immunodeficiency virus type 1 antibodies 2F5 and 2G12. Journal of ...

This second of four exclusive episodes explores whether sparsentan can leapfrog renin-angiotensin system (RAS) blockade and ...

Researchers used AI models to design antibodies that neutralize over 1,300 SARS-CoV-2 strains, including Delta and Omicron.

Some practitioners argue that method of treatment claims are easier to obtain for structure–function-defined antibodies, but recent USPTO prosecution histories show that these claims also face ...

The company’s lead drug candidate, JADE101—a monoclonal antibody targeting APRIL for the treatment of IgA nephropathy—is projected to enter clinical trials in the latter half of 2025 ...

Iga Swiatek spoke to the media after losing to Jelena Ostapenko in the Stuttgart Open. / IMAGO / Eibner Iga Swiatek is still the queen of clay, but even her favorite court surface cannot save her ...

only the albumin-based intranasal vaccine gave rise to robust mucosal IgA antibody responses. The study thus suggests that this needle-free, albumin-based vaccine platform may be attractive for ...

Immunoglobulin A nephropathy (also known as IgA nephropathy or Berger's disease) is a condition that causes IgA antibodies to accumulate in the kidneys—leading to damage that affects their blood ...