The most abundant type of antibody in our intestine is immunoglobulin A (IgA) which, once released, recognizes, and binds specific gut bacteria. On average, about 35% of the gut bacteria are ...

IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their ...

Antibodies to erythrocytes or leukocytes could not be found, but a precipitating antibody reactive with IgA in donor and normal human serum was discovered in the patient's serum. This antibody ...

is a condition that causes IgA antibodies to accumulate in the kidneys—leading to damage that affects their blood-filtering function. Each stage of this condition affects your kidneys a bit ...

We read with great interest the study by Wunsch et al 1 published in this issue of Polish Archives of Internal Medicine, which validated the prognostic ability of 2 previously ide ...

There are five main types (isotypes) of antibodies, each with distinct structures and functions: IgG, IgM, IgA, IgE, and IgD. Illustration of the five major antibody (immunoglobulin) types ...

monoclonal antibody, in the territory outside of Greater China. Climb Bio believes CLYM116 is a potential best-in-class approach to address significant unmet need in patients with IgA nephropathy ...

Ipsen and Sutro Biopharma entered a global licensing deal for STRO-003, an ADC targeting ROR1, overexpressed in cancers, marking Ipsen's first ADC portfolio addition.United States, New York, Jan. 31, ...

Transcutaneous immunization, a topical vaccine application, combines the advantages of needle-free delivery while targeting the immunologically rich milieu of the skin. In animal studies, this ...