For several years, researchers have known that hyperactivity of a subset of neurons located in the hypothalamus, called AgRP neurons, is common in mice with diabetes. “These neurons are playing an ...

Vision loss is a complication for many diabetic patients. In patients with diabetic retinopathy, the principal cause of vision loss is the breakdown of the inner blood-retinal barrier (iBRB)—an ...

The persistent hyperglycemic environment leads to metabolic disturbances and immune responses, which activate macrophages and B/T lymphocytes ... infarction following rapamycin treatment in diabetic ...

Bacteroides vulgatus and pantothenic acid were administered to diabetic mice, which demonstrated their effects on sugar preference in mice. The findings revealed a novel regulatory mechanism ...

To investigate this issue, scientists studied how diet and exercise affect health in mice being ... like AMPK activation can influence nerve health, this research brings us closer to effective, ...

This article investigates the role of stimulator of interferon genes (STING) in I/R injury in diabetic mice and further exploring ... STING pathway activation was observed in diabetic I/R hearts ...

Dietary supplements of the amino acid serine may ease diabetes-related nerve pain, according to research in mice. Nearly half of people with diabetes have neuropathy – a condition in which nerve ...

Although the systemic immunosuppression could protect residual β-cells from autoimmune attack and reverse the diabetes ... TGR5 with high affinity and activate glucagon-like peptide and endogenous ...

By treating diabetic mice with the HIF-1α inhibitor PX-478 ... concentrations leads to a cellular hypoxic phenotype with activation of HIF-1α.” HIF-1α regulates the response to hypoxia ...

And sure enough, the cells in the implants remained functional for up to 200 days, keeping the animals’ diabetes in check for that whole time while leaving their immune systems operating just fine.