Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling ...

Vision loss is a complication for many diabetic patients. In patients with diabetic retinopathy, the principal cause of vision loss is the breakdown of the inner blood-retinal barrier (iBRB)—an ...

The researchers conducted their experiments on diabetic mice. They found that low blood sugar, or hypoglycemia, resulted in an accumulation of hypoxia-inducible factor-1⍺ (HIF-1⍺) and HIF-2⍺.

The research, which investigated the phenomenon in diabetic mice, provides insights into the origin of diabetic retinopathy, specifically in patients with episodes of hypoglycemia. Diabetic ...

The Dodgers designated one recently acquired pitcher for assignment Tuesday and promoted another from Triple-A Oklahoma City. Yoendrys Gomez, who made only three appearances out of the Dodgers ...

Six-week-old female NOD mice were treated with BMS-986202 (30 mg/kg) or vehicle for 6 weeks by oral gavage and followed for up to 24 weeks to determine diabetes development. Blood glucose levels were ...

Acute Hemodynamic Measurements to Assess Sympathetic Activation After 15 weeks on HF, mice were subjected to a transcutaneous glomerular filtration rate measurement as described previously. 33 Then, ...

diabetes mellitus, and smoking enhance ROS generation and decrease endothelial NO production. Key molecular events in atherogenesis such as oxidative modification of lipoproteins and phospholipids, ...

Type 2 diabetes (T2D) arises from a complex interplay of multiple ... maps for higher resolution positional cloning (Schwerbel et al., 2020). Female NZO mice from our own colony (NZO/HIBomDife: German ...

Therefore, in this study, we utilized db/db mice, a well-known and established model of type-2 diabetes, obesity, and metabolic syndrome, to determine if contractile dysregulation is present, and if ...