Muscimol, a GABA-A (GABAA) receptor agonist, enhances GABA's inhibitory effect on neuronal activity by activating GABAA ...

This research utilized the BioCAM DupleX and CorePlate ™ 1W 38/60 to gather high-resolution electrophysiological data for characterizing an ACROBiosystems human iPSC-derived cerebral organoid.

While no model perfectly recapitulates the full complexity of a disease, the application of iPSC-derived organoid co-culture approaches to primary patient-derived cells offers a valuable way to study ...

which is crucial for the study of HDLS using human forebrain organoid models. The use of corrected isogenic iPSC lines as controls increases the validity of the mutation-specific observations. In ...

The research team now plans to further develop the organoid models in terms of complexity and make them available to the scientific community. "It is particularly important to us to make our ...

An international team of researchers led by Max Delbrück Center Scientific Director Professor Maike Sander, MD, has for the first time developed an organoid model of human pluripotent stem cell ...

An international research team has developed an innovative organoid research platform that allowed them to closely investigate the cellular antiviral defense mechanisms of mucosal epithelial ...

Autologous iPSC manufacturing has long been one of the most complex challenges in biomanufacturing, involving labor-intensive processes like manual passaging and colony picking that only a limited ...

The successful surgery marks the official initiation of China's first registration-directed clinical trial for an autologous iPSC-derived cell therapy for Parkinson's disease. The one-month ...

The successful surgery marks the official initiation of China's first registration-directed clinical trial for an autologous iPSC-derived cell therapy for Parkinson's disease. The one-month ...