Manufacturing CAR T cells in the laboratory is expensive and time-consuming. An in vivo approach could get the powerful ...

In a leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful ...

Recent research points to the potential utility of a familiar sounding foe–herpes virus–in the fight against cancer.

Scientists produce human DNase1 in yeast for the first time, opening doors to wider clinical use and easier manufacturing.

New AI Tool Reveals Single-Cell Structure of Chromosomes -- In 3D May 28, 2025 — In a major leap forward for genetic and biomedical research, scientists have developed a powerful new artificial ...

T therapies is an expensive business. The fundamental problem is that CAR-T production is not a good fit for centralized manufacturing.

Imagine cells navigating through a complex maze, guided by chemical signals and the physical landscape of their environment.

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

This valuable study investigates how stochastic and deterministic factors are integrated during cellular decision-making, particularly in situations where cells differentiate into distinct fates ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

In this Tools of the Trade article, Wang and Cheng (Deng Lab) describe an improved protocol for the generation of human pluripotent stem cells by chemical reprogramming based on the targeting of ...

Relevance section written by JCO Associate Editor Thomas E. Stinchcombe, MD. The promising data from the ... The uptitration arm was included because preliminary data from the first-in-human trial of ...