In 2013, Lancaster et al. pioneered the generation of human pluripotent stem cell (hPSC)-derived brain organoids, opening a new approach to modelling neurological diseases using 3D organoid systems.

Purpose To assess alterations in cone morphology, retinal sublayer thicknesses and vessel densities (VDs) in eyes with non-pathological high myopia (HM) and their correlation with retinal sensitivity ...

This fundamental study advances our understanding of the role that energy metabolism, specifically anaerobic glycolysis, plays during retinal development. Convincing in vitro genetic and ...

Guillardia theta anion-conducting channelrhodopsin 1 (GtACR1) is a light-gated anion channel and is widely used as a representative optogenetic tool for neuronal silencing. However, its gating ...

The CellXpress.ai system facilitates media exchange, plating, passaging, organoid monitoring, endpoint assay execution, and complex, AI-powered image analysis and decision making..

DOI: 10.1126/science.adu2987 Eduardo Fernández, Nanowires replace lost retinal cells, Science (2025). DOI: 10.1126/science.ady4439 ...

Each organoid contained 15 to 17 different cell types, comparable to a six-week-old embryonic heart, which has 16 cell types. An adult heart has 21 cell types.

Summary: Researchers have developed a retinal prosthesis made of tellurium nanowires that restores partial vision in blind mice and enables near-infrared vision in primates. The implant, woven into a ...

A retinal implant has partly restored vision in blind mice, suggesting it could one day benefit people with conditions such as age-related macular degeneration, which involves a progressive loss ...

Each organoid contained 15 to 17 different cell types, comparable to a six-week-old embryonic heart, which has 16 cell types. An adult heart has 21 cell types.