The FDA has cleared the investigational new drug (IND) application of LP-184 in triple negative breast cancer (TNBC) treatment – a novel small molecule advanced and developed with Lantern’s AI ...

Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing therapeutics targeting metalloenzymes, today announced the company will present data on its ...

The AACR 2025 meeting emphasizes bridging research and patient care, focusing on HER2 targeting, immune checkpoint inhibitors, and CAR therapies. Education sessions will address cell and gene ...

Homologous recombination deficiency (HRD ... of patients without pathogenic mutations in known HR genes but exhibiting genomic scars indicative of HRD led to the FDA approval of the first scar-based ...

Results: Targeting PCNA suppressed DNA damage repair and ... were authenticated by STR profiling regularly every half year. Lentiviral recombination vectors of human PCNA gene (pGV492-PCNA) and its ...

While manipulating gene expression in brain cells holds tremendous ... Taken together, the findings of this study provide valuable insight into how brain-targeting drugs could be designed based on ...

Department of Chemistry, Shanghai Stomatological Hospital, State Key Laboratory of Molecular Engineering of Polymers and Institute of Biomedical Sciences, Fudan University, Shanghai 200433, People’s ...

As a result, the authors say, if the gene fragments are not observable prior ... "Unlike standard, tissue-based analyses of tumor cells, which can only suggest the likelihood of recurrence ...

By Julia Jacobs and Nicholas Bogel-Burroughs Days before she and her husband, the actor Gene Hackman, died at their home, Betsy Arakawa repeatedly searched online about flu- and Covid-like ...

Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China Department of Pharmacy, The First People’s Hospital of ...

MicroRNAs (miRNAs) target specific genes, allowing them to function as post-transcriptional regulators of gene expression. Oncogene-targeting miRNAs ... reported fecal-based miRNAs used as ...