These ES cells are heterozygous for the knockout mutation. Although these cells will grow and divide in culture, they cannot form an embryo that will develop into a mouse on their own. Step 4 ...

RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in ...

A new model mouse for the neurodegenerative disorder has helped uncover the protective mechanism of a genetic mutation Figure 1: A micrograph showing inflammatory responses in the cortex of the new ...