Positive early stage data for Verve Therapeutics Inc.’s base editing therapy points to a range of development options, including bringing partner Eli Lilly and Co. in a little closer. Verve’s Heart-2 ...

organisms such as mice and dogs. Still, similar studies in humans are minimal and, till now, remain inconclusive. Recent whole-exome sequence data suggest the presence of two rare heterozygous IGF ...

In this study, we leverage serial SEM and deep learning-based image analysis to create a high-resolution map of myelinated axons in the corpus callosum of Shank3B heterozygous mouse. By uncovering ...

Taking all these findings together, the present study revealed that APS therapy could improve cardiomyopathy in STZ-induced diabetic mice and heterozygous SOD2+/- knockout mice with reduced cardiac ...

smmu.edu.cn, zhsli{at}81890.net Recent publication of Hegyi and Sahin-Tóth reported that CPA1 p.n256K mutant mice developed chronic pancreatitis (CP) through endoplasmic reticulum stress.1 This, along ...

Additionally, ovarian reserve was evaluated in heterozygous Ckap5 knockout mice, alongside the ovarian and oocyte single-cell transcriptome analysis. The regulatory mechanism of CKAP5 was studied ...

Using a mouse model, they identified early ... Their analysis revealed compound heterozygous mutations, c.854A>G (p.Asn285Ser) and c.1183C>T (p.Arg395Cys), alongside alterations in metabolic, immune, ...

This valuable study combines real-time keypoint tracking with transdermal activation of sensory neurons to investigate sensory neuron recruitment in freely moving mice, and builds on the authors' ...

A new international study found that a particular form of intermittent fasting boosted the libido of male mice, raising questions about whether it could trigger a similar effect in humans.

As the temperatures rise, you may catch sight of rats or mice scurrying around your garden, as spring is a prime breeding season for these rodents, leading to an increase in their numbers.