The paper, titled “The integrity of the intradimer interface of the Hepatitis B Virus capsid protein dimer regulates capsid self-assembly,” can be viewed on the journal’s website. For doctoral student ...

The capsid of the hepatitis B virus has a very unique structure. It is composed of many monomers which interact to provide flexibility to its structure and function. Hepatitis B virus (HBV ...

ALT: Alanine aminotransferase; SD: Standard deviation. Typical acute hepatitis A virus (HAV) infection is accurately diagnosed by anti-HAV IgM detection. Molecular detection of HAV and anti-HAV ...

Additionally, in vitro data presented for ABI-4334 provide further insights into the potential for next-generation capsid assembly ... candidate for hepatitis D virus (HDV) infection The late ...

This mutation affects the capsid protein, which is essential ... infectious virus particles," adds Eike Steinmann. The hepatitis E virus (HEV) is the main cause of acute viral hepatitis.

Common symptoms of liver inflammation caused by hepatitis E viruses (HEV ... In addition, the data collected indicates that the capsid is not necessarily required for the release of genetic ...

a next-generation capsid assembly modulator (CAM) candidate in development for the treatment of chronic hepatitis B virus (HBV) infection. Chronic HBV (cHBV) infection is a leading cause of ...

The lipid bilayer of the virion envelope incorporates the large (42-kD) hepatitis B virus surface protein ... therapeutic agents, capsid assembly modulators (CAMs), and nucleic acid polymers ...